Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013979 | 0.89 | ITGB3 (0.49) | ALDH1A1ITGB3ITGA2BPTGDR2SMN1; SMN2 | |
| SCHEMBL2014049 | 0.89 | ITGB3 (0.42) | ALDH1A1ITGB3ITGA2BPTGDR2SMN1; SMN2 | |
| SCHEMBL2011666 | 0.87 | ITGB3 (0.46) | ALDH1A1ITGB3ITGA2BSMN1; SMN2RAB9A | |
| SCHEMBL2009624 | 0.87 | ITGB3 (0.41) | ALDH1A1ITGB3ITGA2BPTGDR2SMN1; SMN2 | |
| SCHEMBL2006749 | 0.79 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2RAB9ANPC1GPR119 | |
| SCHEMBL2008007 | 0.78 | ITGB3 (0.42) | ALDH1A1ITGB3ITGA2BMAPT | |
| SCHEMBL2012689 | 0.77 | ALK (0.45) | ALDH1A1ITGB3ITGA2BMAPT | |
| SCHEMBL2008928 | 0.77 | AOC3 (0.42) | ALDH1A1ITGB3ITGA2BRAB9ANPC1 | |
| SCHEMBL2008790 | 0.75 | ITGB3 (0.39) | ALDH1A1ITGB3ITGA2BRAB9ANPC1 | |
| SCHEMBL2009623 | 0.75 | ALDH1A1 (0.36) | ALDH1A1PTGDR2SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964628-B2 | Fibrinogen receptor antagonists and their use | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-06-21 | — | — | US | disclosed |
| US-20100256161-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-10-07 | — | — | US | disclosed |
| US-7759387-B2 | Fibrinogen receptor antagonists and their use | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-07-20 | — | — | US | disclosed |
| US-20070021489-A1 | Fibrinogen receptor antagonists and their use | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256161-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | FGB, F13B, F2 | ALDH1A1 2548/4885ITGB3 169/4885ITGA2B 63/4885 |
| US-20070021489-A1 | Fibrinogen receptor antagonists and their use | FGB, F13B, F2 | ALDH1A1 2548/4885ITGB3 169/4885ITGA2B 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.