Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | RBP4 | P02753 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857040 | 0.93 | AKR1C3 (0.64) | AKR1C3GRM5MEN1KMT2AMAPT | |
| SCHEMBL27486756 | 0.83 | AKR1C3 (0.74) | AKR1C3GRM5MEN1KMT2AMAPT | |
| SCHEMBL16586727 | 0.83 | TSHR (0.59) | AKR1C3MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL27237946 | 0.82 | DRD2 (0.60) | AKR1C3DRD2DRD4DRD3NOTUM | |
| SCHEMBL3709763 | 0.81 | SCD5 (0.54) | AKR1C3GRM5MEN1KMT2AMAPT | |
| SCHEMBL30407939 | 0.80 | ADRB1 (0.65) | AKR1C3MAPTMAPK1RAB9AHTR1A | |
| SCHEMBL5235579 | 0.80 | MEN1 (0.59) | AKR1C3MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL17276412 | 0.80 | AKR1C3 (0.64) | AKR1C3GRM5MEN1KMT2AMAPT | |
| SCHEMBL1491206 | 0.80 | KMT2A (0.64) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27237926 | 0.79 | AKR1C3 (0.49) | AKR1C3GRM5MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |