Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139710 | 0.83 | RORC (0.58) | RORCNR1I2 | |
| SCHEMBL23683608 | 0.83 | RORC (0.58) | RORCNR1I2 | |
| SCHEMBL23112637 | 0.71 | LMNA (0.43) | RORCDRD1 | |
| SCHEMBL23112760 | 0.70 | LMNA (0.42) | RORC | |
| SCHEMBL23112618 | 0.70 | LMNA (0.42) | RORC | |
| SCHEMBL20139636 | 0.70 | RORC (0.58) | RORCNR1I2 | |
| SCHEMBL23683600 | 0.70 | RORC (0.58) | RORCNR1I2 | |
| SCHEMBL20149072 | 0.69 | RORC (0.50) | RORC | |
| SCHEMBL20140441 | 0.68 | RORC (0.80) | RORC | |
| SCHEMBL20139603 | 0.68 | RORC (0.80) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538522-A1 | ROR GAMMA MODULATORS | Bristol-Myers Squibb Company (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |