Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.39 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141652 | 0.83 | HDAC1 (0.47) | MAP4K4HDAC1GPR119SUV39H2NR1H2 | |
| SCHEMBL20141654 | 0.83 | HDAC1 (0.47) | MAP4K4HDAC1GPR119SUV39H2NR1H2 | |
| SCHEMBL5205461 | 0.83 | IDO1 (0.48) | GPR119IDO1MAPTBCHE | |
| SCHEMBL30885785 | 0.83 | IDO1 (0.48) | GPR119IDO1MAPTBCHE | |
| SCHEMBL28520979 | 0.82 | MAP4K4 (0.49) | MAP4K4HDAC1GPR119SUV39H2NR1H2 | |
| SCHEMBL23602022 | 0.79 | MAP4K4 (0.53) | MAP4K4HDAC1GPR119SUV39H2NR1H2 | |
| SCHEMBL13999776 | 0.78 | HDAC1 (0.49) | MAP4K4HDAC1GPR119NR1H2NR1H3 | |
| SCHEMBL13384125 | 0.78 | HDAC1 (0.54) | MAP4K4HDAC1GPR119SUV39H2NR1H2 | |
| SCHEMBL28600264 | 0.78 | DRD2 (0.50) | MAP4K4HDAC1GPR119SUV39H2 | |
| SCHEMBL29799403 | 0.78 | DRD2 (0.50) | MAP4K4HDAC1GPR119SUV39H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |