Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 5/20 | 0.47 |
| ▸ | RPTOR | Q8N122 | 5/20 | 0.47 |
| ▸ | MLST8 | Q9BVC4 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156964 | 0.88 | MTOR (0.49) | MTORRPTORMLST8KDM4ELMNA | |
| SCHEMBL20140388 | 0.87 | MTOR (0.47) | MTORRPTORMLST8SLC27A1RET | |
| SCHEMBL20141707 | 0.85 | MTOR (0.47) | MTORRPTORMLST8KDM4EPARP1 | |
| SCHEMBL20140541 | 0.84 | MTOR (0.46) | MTORRPTORMLST8SLC27A1ALDH1A1 | |
| SCHEMBL20139934 | 0.84 | PPARG (0.47) | MTORRPTORMLST8KDM4EHTT | |
| SCHEMBL20159153 | 0.84 | MTOR (0.61) | MTORRPTORMLST8SLC27A1RET | |
| SCHEMBL20140669 | 0.82 | PARP1 (0.45) | MTORRPTORMLST8KDM4ELMNA | |
| SCHEMBL20157251 | 0.82 | PARP1 (0.49) | MTORRPTORMLST8KDM4ESMN1; SMN2 | |
| SCHEMBL20140021 | 0.82 | PRKAA2 (0.42) | MTORRPTORMLST8KDM4ESLC27A1 | |
| SCHEMBL20156970 | 0.81 | PRKAA2 (0.47) | MTORRPTORMLST8RETPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |