Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.42 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157251 | 0.92 | PARP1 (0.49) | PRKAA2PARP1MTORRPTORMLST8 | |
| SCHEMBL20139934 | 0.90 | PPARG (0.47) | PRKAA2PARP1RETMTORRPTOR | |
| SCHEMBL20140541 | 0.89 | MTOR (0.46) | PRKAA2PARP1HSD17B10RETTACR3 | |
| SCHEMBL20140021 | 0.88 | PRKAA2 (0.42) | PRKAA2PARP1HSD17B10TACR3MTOR | |
| SCHEMBL20140668 | 0.87 | CHRM4 (0.51) | RETMTORRPTORMLST8 | |
| SCHEMBL20156969 | 0.87 | CHRM4 (0.51) | RETMTORRPTORMLST8 | |
| SCHEMBL20140585 | 0.84 | PPARG (0.47) | PARP1MEN1KMT2ARETTACR3 | |
| SCHEMBL20140010 | 0.83 | MTOR (0.44) | PRKAA2PARP1RETTACR3MTOR | |
| SCHEMBL20156964 | 0.82 | MTOR (0.49) | PRKAA2PARP1RETMTORRPTOR | |
| SCHEMBL20156887 | 0.82 | PPARG (0.46) | PARP1RETMTORRPTORMLST8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |