Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SCD | O00767 | 4/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MELK | Q14680 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140074 | 0.85 | MAPT (0.50) | ALDH1A1MAPTNPY2RHRH3L3MBTL1 | |
| SCHEMBL20140860 | 0.84 | MAPT (0.49) | ALDH1A1MAPTNPY2RHRH3L3MBTL1 | |
| SCHEMBL16769733 | 0.76 | HRH3 (0.55) | ALDH1A1MAPTNPY2RHRH3L3MBTL1 | |
| SCHEMBL326799 | 0.74 | LMNA (0.55) | ALDH1A1MAPTNPY2RHRH3L3MBTL1 | |
| SCHEMBL20139878 | 0.74 | PRKAA2 (0.43) | ALDH1A1MAPTNPY2RPRKAA2CHRM4 | |
| SCHEMBL18248410 | 0.73 | KDM4E (0.60) | ALDH1A1MAPTNPY2RHRH3L3MBTL1 | |
| SCHEMBL326931 | 0.72 | L3MBTL1 (0.58) | ALDH1A1MAPTHRH3L3MBTL1POLB | |
| SCHEMBL1999758 | 0.71 | HRH3 (0.51) | HRH3GPR119CHRM4TDO2 | |
| SCHEMBL20729339 | 0.70 | CHRM4 (0.54) | ALDH1A1MAPTNPY2RHRH3L3MBTL1 | |
| SCHEMBL18101815 | 0.70 | NOTUM (0.62) | HRH3GPR119KDM4ECHRM4ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |