Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 5/20 | 0.43 |
| ▸ | RPTOR | Q8N122 | 5/20 | 0.43 |
| ▸ | MLST8 | Q9BVC4 | 5/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC27A1 | Q6PCB7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156964 | 0.88 | MTOR (0.49) | PRKAA2MTORRPTORMLST8PPARG | |
| SCHEMBL20141707 | 0.85 | MTOR (0.47) | PRKAA2MTORRPTORMLST8PPARG | |
| SCHEMBL20140070 | 0.84 | MTOR (0.47) | MTORRPTORMLST8CHRM4PPARG | |
| SCHEMBL20140048 | 0.84 | MTOR (0.47) | MTORRPTORMLST8CHRM4PPARG | |
| SCHEMBL20140046 | 0.84 | MTOR (0.47) | MTORRPTORMLST8CHRM4PPARG | |
| SCHEMBL20156997 | 0.81 | MTOR (0.44) | PRKAA2MTORRPTORMLST8PPARG | |
| SCHEMBL20141897 | 0.80 | HTT (0.47) | PPARGALDH1A1RET | |
| SCHEMBL20157265 | 0.80 | RET (0.40) | PPARGRET | |
| SCHEMBL20140388 | 0.79 | MTOR (0.47) | MTORRPTORMLST8PPARGSLC27A1 | |
| SCHEMBL20139989 | 0.78 | MTOR (0.49) | MTORRPTORMLST8ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |