Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.76 |
| ▸ | LMNA | P02545 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 4/20 | 0.68 |
| ▸ | USP2 | O75604 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15347660 | 0.87 | ALDH1A1 (1.00) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL2376640 | 0.82 | L3MBTL1 (0.55) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL16344196 | 0.82 | GAA (0.59) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL10724385 | 0.82 | ALDH1A1 (1.00) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL2375485 | 0.81 | ALDH1A1 (0.55) | ALDH1A1LMNAKMT2AHTTMAPT | |
| SCHEMBL20140579 | 0.81 | ALDH1A1 (0.64) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL20140910 | 0.80 | ALDH1A1 (0.62) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL2379156 | 0.79 | CNR1 (0.51) | ALDH1A1LMNAMEN1KMT2AHTT | |
| SCHEMBL28810515 | 0.77 | ALDH1A1 (0.56) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL2377343 | 0.77 | FNTA (0.47) | ALDH1A1LMNAMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |