Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140910 | 0.88 | ALDH1A1 (0.62) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL20140025 | 0.81 | ALDH1A1 (0.76) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL10724385 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL2932047 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL20140026 | 0.77 | KDM4E (0.57) | ALDH1A1MEN1KMT2AUSP2LMNA | |
| SCHEMBL20142393 | 0.75 | MEN1 (0.56) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL12189576 | 0.75 | HTT (0.60) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL9565911 | 0.74 | ALDH1A1 (0.81) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL27295608 | 0.73 | ALDH1A1 (0.76) | ALDH1A1TSHRMEN1KMT2AUSP2 | |
| SCHEMBL13116745 | 0.73 | ALDH1A1 (0.68) | ALDH1A1TSHRMEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |