Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | PTGIR | P43119 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140432 | 0.92 | CKS1B (0.45) | CKS1BSKP1SKP2PTGIRDRD2 | |
| SCHEMBL20140039 | 0.83 | CKS1B (0.44) | CKS1BSKP1SKP2PTGIRDRD2 | |
| SCHEMBL30239588 | 0.77 | CYP3A4 (0.47) | CKS1BSKP1SKP2DRD2SIGMAR1 | |
| SCHEMBL24931121 | 0.75 | ALDH1A1 (0.45) | HDAC3HDAC1HDAC8HDAC6SIGMAR1 | |
| SCHEMBL1313637 | 0.74 | BRD9 (0.46) | CKS1BSKP1SKP2DRD2SIGMAR1 | |
| SCHEMBL20140446 | 0.74 | PTGIR (0.44) | PTGIRSMN1; SMN2MEN1LMNAHTT | |
| SCHEMBL28256776 | 0.72 | NQO2 (0.54) | CKS1BSKP1SKP2DRD2HDAC3 | |
| SCHEMBL17619511 | 0.72 | ALDH1A1 (0.56) | CKS1BSKP1SKP2DRD2SMN1; SMN2 | |
| SCHEMBL1949387 | 0.71 | CKS1B (0.47) | CKS1BSKP1SKP2DRD2SIGMAR1 | |
| SCHEMBL15936752 | 0.71 | PDK2 (0.46) | CKS1BSKP1SKP2DRD2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |