Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157345 | 0.92 | CHRM4 (0.41) | GRM1PARP1CHRM4GPR6 | |
| SCHEMBL20157350 | 0.92 | CHRM4 (0.41) | GRM1PARP1CHRM4GPR6 | |
| SCHEMBL20157311 | 0.91 | GRM1 (0.43) | GRM1PARP1TNK2TNK1KDM4E | |
| SCHEMBL20157300 | 0.90 | MTOR (0.43) | GRM1PARP1KDM4EALDH1A1CHRM4 | |
| SCHEMBL20157302 | 0.90 | MTOR (0.43) | GRM1PARP1KDM4EALDH1A1CHRM4 | |
| SCHEMBL20140262 | 0.88 | KDM4E (0.49) | PARP1TNK2TNK1KDM4EALDH1A1 | |
| SCHEMBL20141840 | 0.88 | GRM1 (0.49) | GRM1PARP1TNK2TNK1KDM4E | |
| SCHEMBL20157004 | 0.83 | CHRM4 (0.47) | GRM1KDM4EALDH1A1CHRM4 | |
| SCHEMBL20157005 | 0.83 | CHRM4 (0.47) | GRM1KDM4EALDH1A1CHRM4 | |
| SCHEMBL20157309 | 0.82 | MTOR (0.47) | GRM1PARP1TNK2TNK1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |