Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.41 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157350 | 1.00 | CHRM4 (0.41) | CHRM4MTORRPTORMLST8TRPV1 | |
| SCHEMBL20140106 | 0.92 | GRM1 (0.47) | CHRM4PARP1GPR6GRM1 | |
| SCHEMBL20157542 | 0.88 | CHRM4 (0.49) | CHRM4TRPV1CHRM2CHRM1GRM1 | |
| SCHEMBL20157309 | 0.86 | MTOR (0.47) | CHRM4MTORRPTORMLST8TRPV1 | |
| SCHEMBL20156810 | 0.86 | MTOR (0.47) | CHRM4MTORRPTORMLST8TRPV1 | |
| SCHEMBL20157302 | 0.84 | MTOR (0.43) | CHRM4MTORRPTORMLST8PARP1 | |
| SCHEMBL20157300 | 0.84 | MTOR (0.43) | CHRM4MTORRPTORMLST8PARP1 | |
| SCHEMBL20157308 | 0.84 | CHRM4 (0.44) | CHRM4TRPV1CHRM2HCRTR2MALT1 | |
| SCHEMBL20157311 | 0.83 | GRM1 (0.43) | CHRM4PARP1GRM1 | |
| SCHEMBL20140262 | 0.80 | KDM4E (0.49) | MTORRPTORMLST8PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |