Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.57 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141221 | 0.91 | CHRM2 (0.49) | CHRM2GRM1MAPTCHRM4CHRM1 | |
| SCHEMBL20157102 | 0.84 | CHRM2 (0.52) | CHRM2GRM1MAPTCHRM4CHRM1 | |
| SCHEMBL20139939 | 0.80 | GRM1 (0.67) | CHRM2GRM1CHRM4 | |
| SCHEMBL20139953 | 0.79 | CHRM2 (0.46) | CHRM2GRM1MAPTCHRM4CHRM1 | |
| SCHEMBL20140937 | 0.77 | MTOR (0.55) | CHRM2GRM1MAPTCHRM4CHRM1 | |
| SCHEMBL20140533 | 0.77 | CHRM2 (0.46) | CHRM2GRM1MAPTCHRM4CHRM1 | |
| SCHEMBL20157101 | 0.77 | CHRM2 (0.46) | CHRM2GRM1MAPTCHRM4CHRM1 | |
| SCHEMBL25330081 | 0.76 | GRM1 (0.44) | CHRM2GRM1MAPTCHRM4CHRM1 | |
| SCHEMBL20140806 | 0.76 | NR1H2 (0.46) | CHRM2GRM1MAPTCHRM1ALDH1A1 | |
| SCHEMBL20140684 | 0.76 | MTOR (0.51) | CHRM2GRM1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |