Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 4/20 | 0.39 |
| ▸ | RPTOR | Q8N122 | 4/20 | 0.39 |
| ▸ | MLST8 | Q9BVC4 | 4/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140506 | 1.00 | CHRM2 (0.43) | CHRM2GRM1MTORRPTORMLST8 | |
| SCHEMBL20156864 | 0.88 | MTOR (0.47) | MTORRPTORMLST8MAPTP2RX7 | |
| SCHEMBL20141394 | 0.88 | MTOR (0.42) | CHRM2GRM1MTORRPTORMLST8 | |
| SCHEMBL20141393 | 0.88 | MTOR (0.42) | CHRM2GRM1MTORRPTORMLST8 | |
| SCHEMBL20140684 | 0.83 | MTOR (0.51) | CHRM2GRM1MTORRPTORMLST8 | |
| SCHEMBL20156938 | 0.83 | MTOR (0.51) | CHRM2GRM1MTORRPTORMLST8 | |
| SCHEMBL20140022 | 0.79 | CHRM2 (0.49) | CHRM2GRM1MTORRPTORMLST8 | |
| SCHEMBL20140800 | 0.79 | CHRM2 (0.53) | CHRM2GRM1MTORRPTORMLST8 | |
| SCHEMBL20140571 | 0.79 | DRD4 (0.39) | MTORRPTORMLST8MAPTP2RX7 | |
| SCHEMBL20140629 | 0.79 | CHRM2 (0.49) | CHRM2GRM1MTORRPTORMLST8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |