Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.42 |
| ▸ | RPTOR | Q8N122 | 3/20 | 0.42 |
| ▸ | MLST8 | Q9BVC4 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 12/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141393 | 1.00 | MTOR (0.42) | MTORRPTORMLST8CHRM2P2RX7 | |
| SCHEMBL20157107 | 0.89 | MTOR (0.52) | MTORRPTORMLST8P2RX7 | |
| SCHEMBL20140508 | 0.88 | CHRM2 (0.43) | MTORRPTORMLST8CHRM2P2RX7 | |
| SCHEMBL20140506 | 0.88 | CHRM2 (0.43) | MTORRPTORMLST8CHRM2P2RX7 | |
| SCHEMBL20156864 | 0.76 | MTOR (0.47) | MTORRPTORMLST8P2RX7 | |
| SCHEMBL20141643 | 0.76 | P2RX7 (0.43) | P2RX7TRPV1 | |
| SCHEMBL20140384 | 0.73 | MALT1 (0.41) | P2RX7TRPV1 | |
| SCHEMBL20156938 | 0.72 | MTOR (0.51) | MTORRPTORMLST8CHRM2GRM1 | |
| SCHEMBL20140684 | 0.72 | MTOR (0.51) | MTORRPTORMLST8CHRM2GRM1 | |
| SCHEMBL20139953 | 0.72 | CHRM2 (0.46) | MTORRPTORMLST8CHRM2GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |