Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | LCAT | P04180 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3075144 | 0.95 | PARP1 (0.42) | PARP1CTSSGAAL3MBTL1MGLL | |
| SCHEMBL2962315 | 0.80 | SMN1; SMN2 (0.48) | CTSSGAAL3MBTL1ALDH1A1LMNA | |
| SCHEMBL26127143 | 0.79 | CTSS (0.46) | PARP1CTSSPANK3PARP2 | |
| SCHEMBL21730194 | 0.79 | CTSS (0.46) | PARP1CTSSL3MBTL1LCATCNR1 | |
| SCHEMBL29907703 | 0.79 | CTSS (0.46) | PARP1CTSSL3MBTL1LCATCNR1 | |
| SCHEMBL21730383 | 0.79 | CTSS (0.46) | PARP1CTSSLCATCNR1MEN1 | |
| SCHEMBL29907742 | 0.78 | HTR3A (0.60) | ALDH1A1TSHR | |
| SCHEMBL3467768 | 0.78 | HTR3A (0.60) | ALDH1A1TSHR | |
| SCHEMBL2949577 | 0.78 | CTSS (0.45) | PARP1CTSSL3MBTL1CNR1ALDH1A1 | |
| SCHEMBL19748343 | 0.78 | PANK3 (0.59) | PANK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |