Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25416171 | 0.78 | HCRTR1 (0.43) | KDM4ELMNAKMT2AMEN1MAPT | |
| SCHEMBL3765928 | 0.76 | ITGB2 (0.44) | HSD17B10ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL13162797 | 0.73 | GPR119 (0.46) | HPGDUSP2KDM4ENPSR1HSD17B10 | |
| SCHEMBL13162793 | 0.71 | KDM4E (0.35) | HPGDUSP2KDM4ENPSR1HSD17B10 | |
| SCHEMBL16795197 | 0.71 | PHGDH (0.44) | NCF1HPGDUSP2KDM4ENPSR1 | |
| SCHEMBL18711785 | 0.71 | ITGB2 (0.47) | HPGDNPSR1HSD17B10ALDH1A1GBA1 | |
| SCHEMBL23243032 | 0.70 | ALDH1A1 (0.40) | HPGDKDM4EHSD17B10ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL28658794 | 0.70 | CHRM4 (0.47) | LMNAKMT2AHTTGAASMN1; SMN2 | |
| SCHEMBL13270551 | 0.69 | CHRM3 (0.33) | — | |
| SCHEMBL18702044 | 0.68 | SPR (0.44) | HPGDALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |