Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.33 |
| ▸ | CETP | P11597 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663428 | 0.85 | ALDH1A1 (0.35) | CTSLCTSSALDH1A1CYP3A4TSHR | |
| SCHEMBL1664003 | 0.84 | ALDH1A1 (0.40) | CTSLCTSSALDH1A1CYP3A4TSHR | |
| SCHEMBL1664348 | 0.83 | BLM (0.35) | ALDH1A1TSHRSIRT2SIRT1PRSS1 | |
| SCHEMBL1664495 | 0.75 | CETP (0.34) | CTSLCTSSALDH1A1CYP3A4TSHR | |
| SCHEMBL16344715 | 0.74 | MME (0.41) | CTSLALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL2940788 | 0.71 | SIRT2 (0.32) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL1665168 | 0.71 | ALDH1A1 (0.35) | CTSLCTSSALDH1A1CYP3A4TSHR | |
| SCHEMBL1664908 | 0.71 | CETP (0.35) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL1665095 | 0.70 | ADAM17 (0.34) | CTSLCTSSALDH1A1CYP3A4TSHR | |
| SCHEMBL1666301 | 0.70 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011071674-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2011-06-16 | — | — | WO | disclosed |