Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.37 |
| ▸ | CETP | P11597 | 3/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014071 | 0.84 | CTSL (0.35) | ALDH1A1TDP1CYP3A4TSHRMAPK1 | |
| SCHEMBL1666301 | 0.82 | ALDH1A1 (0.40) | ALDH1A1TDP1CYP3A4TSHRMAPK1 | |
| SCHEMBL1663446 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TDP1CYP3A4TSHRMAPK1 | |
| SCHEMBL1663428 | 0.70 | ALDH1A1 (0.35) | ALDH1A1TDP1CYP3A4TSHRMAPK1 | |
| SCHEMBL16344589 | 0.69 | CETP (0.50) | ALDH1A1TDP1CYP3A4TSHRMAPK1 | |
| SCHEMBL23912192 | 0.68 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHRMAPK1L3MBTL1 | |
| SCHEMBL20879996 | 0.66 | DDB1 (0.44) | ALDH1A1TDP1MAPK1L3MBTL1DDB1 | |
| SCHEMBL1664673 | 0.66 | ALDH1A1 (0.39) | ALDH1A1TDP1CYP3A4TSHRMAPK1 | |
| SCHEMBL25317306 | 0.66 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRMAPK1L3MBTL1 | |
| SCHEMBL32674206 | 0.66 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011071674-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2011-06-16 | — | — | WO | disclosed |
| EP-2307476-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009152068-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2009-12-17 | — | — | WO | disclosed |