Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157263 | 0.81 | NQO2 (0.44) | SIGMAR1NQO2NAMPT | |
| SCHEMBL21591743 | 0.79 | SIGMAR1 (0.48) | SIGMAR1SYKBACE1TMEM97HTT | |
| SCHEMBL19211125 | 0.79 | SIGMAR1 (0.52) | SIGMAR1SYKTMEM97HTTMEN1 | |
| SCHEMBL19212187 | 0.77 | SIGMAR1 (0.46) | SIGMAR1TMEM97HTTP2RX7MEN1 | |
| SCHEMBL28697175 | 0.76 | SIGMAR1 (0.43) | SIGMAR1SYKBACE1HTTMEN1 | |
| SCHEMBL514343 | 0.76 | SIGMAR1 (0.61) | SIGMAR1SYKHTTMEN1KMT2A | |
| SCHEMBL20140683 | 0.76 | MEN1 (0.48) | SIGMAR1CTSSCTSLTMEM97MEN1 | |
| SCHEMBL19212437 | 0.76 | SIGMAR1 (0.48) | SIGMAR1TMEM97 | |
| SCHEMBL28698227 | 0.76 | MAPT (0.48) | SIGMAR1SYKBACE1HTTP2RX7 | |
| SCHEMBL28682343 | 0.74 | SIGMAR1 (0.44) | SIGMAR1SYKBACE1HTTP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |