Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | TGM1 | P22735 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28698227 | 0.86 | MAPT (0.48) | SIGMAR1NAMPTBACE1MEN1KMT2A | |
| SCHEMBL28683481 | 0.85 | PDK1 (0.39) | SIGMAR1NPSR1MAPTALDH1A1LMNA | |
| SCHEMBL21591743 | 0.81 | SIGMAR1 (0.48) | SIGMAR1NAMPTBACE1MEN1KMT2A | |
| SCHEMBL19211125 | 0.81 | SIGMAR1 (0.52) | SIGMAR1NAMPTMEN1KMT2ANPSR1 | |
| SCHEMBL21457818 | 0.80 | BACE1 (0.48) | BACE1MEN1KMT2ANPSR1HTT | |
| SCHEMBL28682343 | 0.79 | SIGMAR1 (0.44) | SIGMAR1NAMPTBACE1MEN1KMT2A | |
| SCHEMBL28683499 | 0.79 | BACE1 (0.47) | BACE1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL2449157 | 0.77 | BACE1 (0.50) | NAMPTBACE1MEN1KMT2A | |
| SCHEMBL20140730 | 0.76 | SIGMAR1 (0.43) | SIGMAR1NAMPTBACE1MEN1KMT2A | |
| SCHEMBL19212401 | 0.76 | P2RY12 (0.54) | BACE1MEN1KMT2AP2RY12SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-B | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | 瓦洛健康公司 | 2022-01-14 | — | — | CN | disclosed |