Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.41 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133633 | 0.83 | KCNA3 (0.49) | ALDH1A1KDM4ESSTR4 | |
| SCHEMBL22686240 | 0.82 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1SIGMAR1C5AR1 | |
| SCHEMBL31042527 | 0.80 | DRD4 (0.51) | ALDH1A1KDM4EMTORRPTORMLST8 | |
| SCHEMBL20133634 | 0.79 | MTOR (0.59) | ALDH1A1KDM4EDPP4DPP8DPP9 | |
| SCHEMBL25267978 | 0.78 | NOTUM (0.45) | — | |
| SCHEMBL17188024 | 0.78 | NOTUM (0.45) | — | |
| SCHEMBL20140893 | 0.78 | MTOR (0.42) | ALDH1A1KDM4EDPP4DPP8DPP9 | |
| SCHEMBL20129624 | 0.77 | KDM4E (0.56) | ALDH1A1KDM4ESSTR4 | |
| SCHEMBL20129616 | 0.77 | KDM4E (0.56) | ALDH1A1KDM4EDPP4DPP8DPP9 | |
| SCHEMBL20141678 | 0.76 | CHRM4 (0.50) | DPP4DPP8DPP9MTORRPTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |