Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140658 | 0.80 | ROCK2 (0.50) | ROCK2ROCK1 | |
| SCHEMBL20140662 | 0.80 | ROCK2 (0.50) | ROCK2ROCK1 | |
| SCHEMBL31651868 | 0.77 | HTR2C (0.56) | HTR2CROCK2ROCK1EPHX2HTR6 | |
| SCHEMBL6637498 | 0.77 | HTR2C (0.56) | HTR2CROCK2ROCK1EPHX2HTR6 | |
| SCHEMBL3690677 | 0.74 | HTR2C (0.69) | HTR2CROCK2ROCK1HTR6 | |
| SCHEMBL3687371 | 0.73 | HTR2C (0.68) | HTR2CROCK2ROCK1 | |
| SCHEMBL13116668 | 0.72 | HTR2C (0.56) | HTR2CEPHX2 | |
| SCHEMBL3680133 | 0.72 | HTR2C (0.67) | HTR2CEPHX2 | |
| SCHEMBL2076366 | 0.72 | HTR2C (1.00) | HTR2CHTR6 | |
| SCHEMBL30040877 | 0.72 | HTR2C (1.00) | HTR2CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |