Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5178563 | 0.82 | MEN1 (0.56) | MEN1KMT2AMEP1B | |
| SCHEMBL13711065 | 0.74 | CES2 (0.44) | PDPK1 | |
| SCHEMBL29500270 | 0.73 | RAB9A (0.49) | MEN1KMT2A | |
| SCHEMBL5680157 | 0.72 | MAOB (0.72) | SCN9AMAOBMAOA | |
| SCHEMBL1070319 | 0.72 | MAOB (0.72) | SCN9AMAOBMAOA | |
| SCHEMBL13707908 | 0.72 | APP (0.43) | ADRB2PDPK1 | |
| SCHEMBL4427598 | 0.72 | CNR2 (0.51) | MEN1KMT2AMAOBMEP1B | |
| SCHEMBL5224347 | 0.72 | CNR2 (0.51) | MEN1KMT2AMAOBMEP1B | |
| SCHEMBL1070627 | 0.71 | BCHE (0.55) | — | |
| SCHEMBL5684150 | 0.71 | MAOB (0.51) | MEN1KMT2ASCN9AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |