Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 12/20 | 0.45 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133687 | 0.85 | POLB (0.49) | — | |
| SCHEMBL24640111 | 0.83 | HRH3 (0.42) | SMOKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL20140857 | 0.82 | ALDH1A1 (0.39) | SMOSLC6A7KMT2AMEN1CHIA | |
| SCHEMBL20133686 | 0.78 | HTR2A (0.46) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL20141349 | 0.77 | SMO (0.45) | SMOSLC6A7KMT2AGRM1SMN1; SMN2 | |
| SCHEMBL24640807 | 0.75 | CHIA (0.41) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3119867 | 0.74 | SLC6A7 (0.43) | SMOSLC6A7GRM1SMN1; SMN2 | |
| SCHEMBL20140855 | 0.74 | GRM1 (0.67) | SMOSLC6A7GRM1SMN1; SMN2CYP3A4 | |
| SCHEMBL27141867 | 0.73 | PARP1 (0.51) | SLC6A7SMN1; SMN2CYP2C19 | |
| SCHEMBL24639820 | 0.73 | HRH3 (0.36) | KMT2ASMN1; SMN2MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |