Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.59 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010730 | 0.90 | HCRTR1 (0.58) | HCRTR1HCRTR2NPC1RAB9AMAOB | |
| SCHEMBL2011442 | 0.90 | HCRTR1 (0.58) | HCRTR1HCRTR2NPC1RAB9AMAOB | |
| SCHEMBL2014644 | 0.90 | HCRTR1 (0.59) | HCRTR1HCRTR2NPC1RAB9APADI4 | |
| SCHEMBL2014998 | 0.90 | HCRTR1 (0.59) | HCRTR1HCRTR2NPC1RAB9APADI4 | |
| SCHEMBL2011116 | 0.84 | HCRTR1 (0.64) | HCRTR1HCRTR2NPC1RAB9AMAOB | |
| SCHEMBL2051271 | 0.84 | HCRTR1 (0.61) | HCRTR1HCRTR2NPC1RAB9AKMT2A | |
| SCHEMBL2012147 | 0.84 | HCRTR1 (0.61) | HCRTR1HCRTR2NPC1RAB9AKMT2A | |
| SCHEMBL2010896 | 0.83 | HCRTR1 (0.58) | HCRTR1HCRTR2NPC1RAB9AKMT2A | |
| SCHEMBL2015468 | 0.83 | HCRTR1 (0.58) | HCRTR1HCRTR2NPC1RAB9APADI4 | |
| SCHEMBL2013146 | 0.83 | HCRTR1 (0.66) | HCRTR1HCRTR2MAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |