Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.58 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014119 | 0.83 | HCRTR1 (0.59) | HCRTR1HCRTR2RAB9ANPC1KMT2A | |
| SCHEMBL2015468 | 0.83 | HCRTR1 (0.58) | HCRTR1HCRTR2RAB9ANPC1HDAC1 | |
| SCHEMBL13139060 | 0.82 | HCRTR1 (0.77) | HCRTR1HCRTR2RAB9ANPC1KMT2A | |
| SCHEMBL2014644 | 0.80 | HCRTR1 (0.59) | HCRTR1HCRTR2RAB9ANPC1HDAC1 | |
| SCHEMBL2014998 | 0.80 | HCRTR1 (0.59) | HCRTR1HCRTR2RAB9ANPC1HDAC1 | |
| SCHEMBL13139102 | 0.80 | HCRTR1 (0.71) | HCRTR1HCRTR2RAB9ANPC1KDM4E | |
| SCHEMBL2017043 | 0.80 | HCRTR1 (0.57) | HCRTR1HCRTR2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2051271 | 0.80 | HCRTR1 (0.61) | HCRTR1HCRTR2RAB9ANPC1ALDH1A1 | |
| SCHEMBL2012147 | 0.80 | HCRTR1 (0.61) | HCRTR1HCRTR2RAB9ANPC1ALDH1A1 | |
| SCHEMBL13139095 | 0.79 | HCRTR1 (0.70) | HCRTR1HCRTR2RAB9ANPC1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | claimed |
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |