Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 4/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141266 | 0.72 | GRM1 (0.51) | GRM1HSD11B1KDM4ERECQLALDH1A1 | |
| SCHEMBL20140861 | 0.72 | GRM1 (0.51) | GRM1HSD11B1KDM4ERECQLALDH1A1 | |
| SCHEMBL20139963 | 0.69 | GRM1 (0.54) | GRM1HSD11B1KDM4ERECQLALDH1A1 | |
| SCHEMBL5482402 | 0.69 | GRM1 (0.66) | GRM1HSD11B1KDM4ERECQLALDH1A1 | |
| SCHEMBL20141549 | 0.68 | GRM1 (0.49) | GRM1HSD11B1KDM4ERECQLALDH1A1 | |
| SCHEMBL5321658 | 0.68 | GRM1 (0.50) | GRM1HSD11B1KDM4ERECQLALDH1A1 | |
| SCHEMBL26117777 | 0.68 | GRM1 (0.58) | GRM1HSD11B1KDM4ERECQLALDH1A1 | |
| SCHEMBL30607641 | 0.68 | GRM1 (0.58) | GRM1HSD11B1KDM4ERECQLALDH1A1 | |
| SCHEMBL20141184 | 0.67 | GRM1 (0.47) | GRM1HSD11B1KDM4ERECQLALDH1A1 | |
| SCHEMBL20142472 | 0.66 | DRD2 (0.42) | GRM1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |