Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 8/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23357843 | 0.83 | GAA (0.39) | OPRL1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL27201548 | 0.82 | MEN1 (0.39) | OPRL1ALDH1A1LMNAHSD11B1 | |
| SCHEMBL5373284 | 0.81 | OPRM1 (0.60) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL1660328 | 0.79 | CA12 (0.45) | OPRM1OPRD1CA12CA1CA2 | |
| SCHEMBL3249164 | 0.79 | GPR119 (0.47) | OPRD1OPRK1 | |
| SCHEMBL23232266 | 0.78 | OPRL1 (0.42) | OPRL1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL30062630 | 0.78 | OPRL1 (0.42) | OPRL1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL795975 | 0.78 | ALDH1A1 (0.56) | OPRL1OPRM1OPRD1OPRK1CA12 | |
| SCHEMBL3326370 | 0.77 | HDAC4 (0.47) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL14153963 | 0.77 | OPRL1 (0.47) | OPRL1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |