Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.36 |
| ▸ | MTOR | P42345 | 3/20 | 0.35 |
| ▸ | RPTOR | Q8N122 | 3/20 | 0.35 |
| ▸ | MLST8 | Q9BVC4 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 3/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141281 | 0.90 | MTOR (0.35) | SLC6A2SLC6A4MTORRPTORMLST8 | |
| SCHEMBL20141483 | 0.87 | TP53 (0.32) | NOTUMSLC6A2SLC6A4MTORRPTOR | |
| SCHEMBL20140898 | 0.85 | SLC6A4 (0.41) | NOTUMSLC6A2SLC6A4SLC6A3P2RY12 | |
| SCHEMBL20141353 | 0.82 | SLC6A2 (0.39) | NOTUMSLC6A2SLC6A4SLC6A3P2RY12 | |
| SCHEMBL20141180 | 0.82 | SLC6A2 (0.41) | NOTUMSLC6A2SLC6A4SLC6A3P2RY12 | |
| SCHEMBL20141074 | 0.80 | SLC6A2 (0.42) | NOTUMSLC6A2SLC6A4SLC6A3NOS2 | |
| SCHEMBL20141597 | 0.80 | MTOR (0.54) | MTORRPTORMLST8 | |
| SCHEMBL20141216 | 0.79 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3NOS2NOS3 | |
| SCHEMBL20141214 | 0.79 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3NOS2NOS3 | |
| SCHEMBL20141181 | 0.79 | SLC6A4 (0.41) | NOTUMSLC6A2SLC6A4SLC6A3P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |