Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141049 | 0.89 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3MAPK14KCNH2 | |
| SCHEMBL20140944 | 0.83 | OPRM1 (0.40) | SLC6A2SLC6A4SLC6A3NOTUM | |
| SCHEMBL20140898 | 0.82 | SLC6A4 (0.41) | SLC6A2SLC6A4SLC6A3NOTUMNOS2 | |
| SCHEMBL20141405 | 0.80 | NOTUM (0.38) | SLC6A2SLC6A4SLC6A3NOTUMNOS2 | |
| Trifluoroacetic Acid SCHEMBL20141119 | 0.78 | MTOR (0.46) | CYP2D6 | |
| SCHEMBL5629597 | 0.77 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3NOS2KCNH2 | |
| SCHEMBL20140936 | 0.77 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3NOTUMNOS2 | |
| SCHEMBL20141738 | 0.77 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3HTTKCNH2 | |
| SCHEMBL20141216 | 0.76 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3NOS2KCNH2 | |
| SCHEMBL20141214 | 0.76 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3NOS2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |