Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129737 | 0.83 | ADRB1 (0.38) | ADRB1CHRNA7 | |
| SCHEMBL20141335 | 0.83 | ADRB1 (0.38) | ADRB1CHRNA7 | |
| SCHEMBL21360312 | 0.81 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL22186925 | 0.76 | ADRB1 (0.33) | ADRB1CHRNA7 | |
| SCHEMBL20142347 | 0.72 | HTR2C (0.43) | — | |
| SCHEMBL27705052 | 0.70 | HDAC8 (0.44) | SLC6A2SLC6A4SLC6A3SLC6A7 | |
| Hydrochloric Acid SCHEMBL10773342 | 0.68 | PLD1 (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20141133 | 0.67 | ADAMTS5 (0.36) | SLC6A2SLC6A3GLSHTR1DSLC6A7 | |
| SCHEMBL20141438 | 0.66 | MTOR (0.45) | GLSHTR1DSLC6A7 | |
| SCHEMBL21360320 | 0.64 | PLD1 (0.54) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |