Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140942 | 0.82 | CKS1B (0.49) | DPP4DPP8DPP7ADORA3ADORA1 | |
| SCHEMBL19664897 | 0.82 | DPP4 (0.47) | DPP4DPP8DPP7GRM5TACR3 | |
| SCHEMBL13677263 | 0.77 | HRH4 (0.47) | DPP4DPP8DPP7NR1H2NR1H3 | |
| SCHEMBL13676974 | 0.73 | OGA (0.45) | DPP4DPP8DPP7NR1H2NR1H3 | |
| SCHEMBL25410612 | 0.73 | DPP4 (0.32) | DPP4DPP8DPP7TSHR | |
| SCHEMBL22092728 | 0.73 | DPP4 (0.32) | DPP4DPP8DPP7TSHR | |
| SCHEMBL19664902 | 0.73 | DPP4 (0.32) | DPP4DPP8DPP7TSHR | |
| SCHEMBL16003887 | 0.72 | PDE10A (0.45) | NR1H2NR1H3TSHRPDE10AMEN1 | |
| SCHEMBL20140943 | 0.72 | ADORA3 (0.40) | DPP4DPP8DPP7NR1H2NR1H3 | |
| SCHEMBL14520436 | 0.71 | NR1H3 (0.43) | DPP4DPP8DPP7NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |