Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141429 | 0.72 | DPP4 (0.54) | ADORA3ADORA1DPP4DPP8DPP7 | |
| SCHEMBL20140942 | 0.68 | CKS1B (0.49) | ADORA3ADORA1DPP4DPP8DPP7 | |
| SCHEMBL3393288 | 0.59 | NR1H2 (0.63) | ADORA1NR1H2NR1H3RAB9ANPC1 | |
| SCHEMBL13677263 | 0.59 | HRH4 (0.47) | ADORA3ADORA1DPP4DPP8DPP7 | |
| SCHEMBL16003887 | 0.58 | PDE10A (0.45) | NR1H2NR1H3TSHRKMT2AALDH1A1 | |
| SCHEMBL3118565 | 0.57 | MTHFD2 (0.50) | TSHR | |
| SCHEMBL4959931 | 0.57 | DRD2 (0.62) | RAB9AHPGDKMT2A | |
| SCHEMBL8650872 | 0.57 | GAA (0.57) | ADORA1NR1H2NR1H3TSHRF2 | |
| SCHEMBL28739860 | 0.56 | P2RX7 (0.55) | ALDH1A1LMNA | |
| SCHEMBL1696532 | 0.56 | LMNA (0.54) | TSHRMAPTHPGDKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |