Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.49 |
| ▸ | SKP1 | P63208 | 2/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933697 | 0.89 | GPR119 (0.47) | CKS1BSKP1SKP2GBA1ESR2 | |
| SCHEMBL31612680 | 0.86 | HDAC4 (0.48) | DPP4DPP8DPP7ESR2ALDH1A1 | |
| SCHEMBL24689567 | 0.85 | NR1H2 (0.43) | DPP4DPP8DPP7ESR2HDAC4 | |
| SCHEMBL15933535 | 0.85 | GPR119 (0.49) | ESR2JAK2JAK3HDAC4GPR119 | |
| SCHEMBL15933643 | 0.85 | GPR119 (0.45) | CKS1BSKP1SKP2GBA1ESR2 | |
| SCHEMBL17984905 | 0.84 | ESR2 (0.40) | CKS1BSKP1SKP2DPP4DPP8 | |
| SCHEMBL15933477 | 0.82 | HDAC4 (0.40) | CKS1BSKP1SKP2DPP4DPP8 | |
| SCHEMBL20141429 | 0.82 | DPP4 (0.54) | DPP4DPP8DPP7ADORA3ADORA1 | |
| SCHEMBL15933537 | 0.82 | GBA1 (0.55) | CKS1BSKP1SKP2GBA1MAPK1 | |
| SCHEMBL15933678 | 0.80 | CSNK1D (0.43) | CKS1BSKP1SKP2DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |