Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31029003 | 0.83 | TSHR (0.66) | TSHRALDH1A1HTTMAPTPOLB | |
| SCHEMBL9931472 | 0.80 | TSHR (0.52) | TSHRALDH1A1HTTMAPTPOLB | |
| SCHEMBL14953233 | 0.78 | ALDH1A1 (0.50) | TSHRALDH1A1HTTMAPTPOLB | |
| SCHEMBL17809495 | 0.74 | GRM2 (0.58) | TSHRALDH1A1HTTL3MBTL1GRM2 | |
| SCHEMBL12369545 | 0.73 | POLB (0.60) | TSHRALDH1A1HTTMAPTPOLB | |
| SCHEMBL24187304 | 0.72 | TSHR (0.52) | TSHRALDH1A1HTTMAPTPOLB | |
| SCHEMBL8355374 | 0.71 | GRM2 (0.50) | TSHRALDH1A1HTTL3MBTL1GRM2 | |
| SCHEMBL20082374 | 0.71 | TSHR (0.51) | TSHRALDH1A1HTTMAPTPOLB | |
| SCHEMBL14191672 | 0.71 | ALDH1A1 (0.56) | TSHRALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL5380065 | 0.71 | SIGMAR1 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |