Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141738 | 0.90 | SLC6A2 (0.40) | SLC6A2SLC6A4CCR8KDM4EALDH1A1 | |
| SCHEMBL20140900 | 0.89 | SLC6A2 (0.41) | SLC6A2SLC6A4DDB1CRBN | |
| SCHEMBL20141026 | 0.89 | NR1I2 (0.41) | SLC6A2SLC6A4CCR8HPGDDDB1 | |
| SCHEMBL20141029 | 0.87 | SLC6A2 (0.38) | SLC6A2SLC6A4GAAKDM4EALDH1A1 | |
| SCHEMBL20141215 | 0.81 | HTR2C (0.39) | SLC6A2SLC6A4HTR2COPRM1OPRD1 | |
| SCHEMBL20141036 | 0.81 | KCNH2 (0.37) | SLC6A2SLC6A4KDM4EALDH1A1HPGD | |
| SCHEMBL20141038 | 0.81 | KCNH2 (0.37) | SLC6A2SLC6A4KDM4EALDH1A1HPGD | |
| SCHEMBL20141147 | 0.81 | SLC6A2 (0.38) | SLC6A2SLC6A4GAAKDM4EALDH1A1 | |
| SCHEMBL20141049 | 0.80 | SLC6A2 (0.38) | SLC6A2SLC6A4ALDH1A1KCNH2 | |
| SCHEMBL20141346 | 0.78 | SLC6A2 (0.44) | SLC6A2SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |