Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | DVL1 | O14640 | 1/20 | 0.33 |
| ▸ | DVL3 | Q92997 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141074 | 0.89 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3HTR6KCNH2 | |
| SCHEMBL20141215 | 0.86 | HTR2C (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20141029 | 0.83 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CHEK1CHEK2 | |
| SCHEMBL20141281 | 0.81 | MTOR (0.35) | SLC6A2SLC6A4SLC6A3CHEK1CHEK2 | |
| SCHEMBL20141613 | 0.80 | SLC6A2 (0.38) | SLC6A2SLC6A4KCNH2ALDH1A1 | |
| SCHEMBL20141036 | 0.78 | KCNH2 (0.37) | SLC6A2SLC6A4SLC6A3CHEK1KCNH2 | |
| SCHEMBL20141038 | 0.78 | KCNH2 (0.37) | SLC6A2SLC6A4SLC6A3CHEK1KCNH2 | |
| SCHEMBL20141147 | 0.77 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CHEK1CHEK2 | |
| SCHEMBL20140944 | 0.77 | OPRM1 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20141101 | 0.76 | CHEK1 (0.36) | CHEK1CHEK2KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |