Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.43 |
| ▸ | RET | P07949 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140820 | 0.83 | LMNA (0.43) | GPR119ALDH1A1LMNAMAPTCKS1B | |
| SCHEMBL5205461 | 0.77 | IDO1 (0.48) | GPR119ALDH1A1LMNAMAPTCKS1B | |
| SCHEMBL30885785 | 0.77 | IDO1 (0.48) | GPR119ALDH1A1LMNAMAPTCKS1B | |
| SCHEMBL5762899 | 0.74 | ACHE (0.47) | GPR119ALDH1A1LMNAMAPTCKS1B | |
| SCHEMBL652792 | 0.74 | GRM5 (0.53) | GPR119ALDH1A1LMNAMAPTCKS1B | |
| SCHEMBL24990173 | 0.74 | MAPT (0.53) | GPR119RETALDH1A1LMNAMAPT | |
| SCHEMBL6098788 | 0.74 | ESR2 (0.48) | GPR119NR1H2IDO1 | |
| Trifluoroacetic Acid SCHEMBL20142184 | 0.73 | IRAK4 (0.41) | ALDH1A1 | |
| SCHEMBL31651879 | 0.73 | EGLN2 (0.44) | GPR119ALDH1A1LMNAMAPTCKS1B | |
| SCHEMBL24989016 | 0.73 | MAPT (0.53) | RETALDH1A1LMNAMAPTNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |