Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156815 | 0.88 | ALDH1A1 (0.40) | ALDH1A1HRH4HTR6 | |
| SCHEMBL20141173 | 0.80 | MEN1 (0.34) | — | |
| Trifluoroacetic Acid SCHEMBL30839779 | 0.75 | BACE1 (0.46) | ALDH1A1HRH4HTR6BACE1 | |
| SCHEMBL20141639 | 0.73 | GPR119 (0.43) | ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3921505 | 0.72 | ALDH1A1 (0.44) | IRAK4ALDH1A1HRH4HTR6BACE1 | |
| Trifluoroacetic Acid SCHEMBL29364273 | 0.72 | KEAP1 (0.47) | BACE1 | |
| SCHEMBL20142186 | 0.72 | HTR6 (0.36) | IRAK4ALDH1A1HTR6 | |
| Trifluoroacetic Acid SCHEMBL3920662 | 0.70 | ALDH1A1 (0.41) | IRAK4ALDH1A1HRH4BACE1 | |
| Trifluoroacetic Acid SCHEMBL27756881 | 0.68 | ADRB1 (0.47) | IRAK4ALDH1A1HRH4HTR6BACE1 | |
| Trifluoroacetic Acid SCHEMBL3919226 | 0.68 | ALDH1A1 (0.60) | IRAK4ALDH1A1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |