Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139839 | 0.78 | MAPT (0.38) | HTR2CKDM4EALDH1A1HPGDHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL20141711 | 0.72 | HTR2C (0.39) | HTR2CBRPF1BRD4ALDH1A1LMNA | |
| SCHEMBL28172901 | 0.69 | KDM4E (0.50) | BRPF1BRD4KDM4EALDH1A1HPGD | |
| SCHEMBL4590419 | 0.68 | PDPK1 (0.40) | BRPF1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL20142186 | 0.66 | HTR6 (0.36) | ALDH1A1HTR6 | |
| SCHEMBL23744700 | 0.66 | HTR2C (0.59) | HTR2CALDH1A1LMNA | |
| SCHEMBL3219375 | 0.66 | HTR2C (0.59) | HTR2CALDH1A1LMNA | |
| SCHEMBL3219365 | 0.66 | HTR2C (0.59) | HTR2CALDH1A1LMNA | |
| SCHEMBL4244446 | 0.66 | HTR6 (0.61) | HTR2CKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30345613 | 0.66 | HTR2C (0.59) | HTR2CALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |