Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KHK | P50053 | 2/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.34 |
| ▸ | GHSR | Q92847 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141712 | 0.78 | HTR2C (0.39) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| Trifluoroacetic Acid SCHEMBL20139838 | 0.72 | TRPV1 (0.41) | MAPTKHKHSD11B1BCL2A1 | |
| SCHEMBL15557018 | 0.70 | HPGD (0.46) | MAPTKHKKDM4EALDH1A1HPGD | |
| SCHEMBL28169823 | 0.68 | HTR1D (0.49) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL4573855 | 0.68 | BRPF1 (0.45) | MAPTKHKTLR9TLR8TLR7 | |
| SCHEMBL3925907 | 0.67 | SLC22A6 (0.64) | ALDH1A1SLC22A6 | |
| SCHEMBL2252323 | 0.66 | CHRM2 (0.42) | MAPTKHKTLR9TLR8TLR7 | |
| SCHEMBL5274632 | 0.66 | CHRM2 (0.42) | MAPTKHKTLR9TLR8TLR7 | |
| SCHEMBL22802008 | 0.66 | NPC1 (0.47) | MAPTKHKALDH1A1HSD17B10BCL2A1 | |
| SCHEMBL3770301 | 0.66 | NPC1 (0.47) | MAPTKHKALDH1A1HSD17B10BCL2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |