Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG7 | O95352 | 19/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142826 | 0.88 | ATG7 (0.46) | ATG7RXFP1 | |
| SCHEMBL20141851 | 0.80 | ATG7 (0.72) | ATG7RXFP1 | |
| SCHEMBL20141925 | 0.79 | PI4KA (0.57) | ATG7RXFP1 | |
| SCHEMBL20142135 | 0.73 | PI4KA (0.59) | ATG7RXFP1 | |
| SCHEMBL20141769 | 0.72 | ATG7 (0.71) | ATG7RXFP1 | |
| SCHEMBL20142034 | 0.71 | ATG7 (0.61) | ATG7 | |
| SCHEMBL20142040 | 0.70 | PI4KA (0.56) | ATG7RXFP1 | |
| SCHEMBL20141770 | 0.70 | ATG7 (0.51) | ATG7RXFP1 | |
| SCHEMBL22778880 | 0.69 | ATG7 (0.72) | ATG7RXFP1 | |
| SCHEMBL20142322 | 0.69 | ATG7 (0.70) | ATG7RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089786-A1 | ATG7 INHIBITORS AND THE USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |