Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG7 | O95352 | 19/20 | 0.61 |
| ▸ | ADK | P55263 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142202 | 0.88 | ATG7 (0.63) | ATG7ADK | |
| SCHEMBL20141736 | 0.88 | ATG7 (0.62) | ATG7ADK | |
| SCHEMBL20141658 | 0.83 | ATG7 (0.68) | ATG7 | |
| SCHEMBL20142826 | 0.82 | ATG7 (0.46) | ATG7 | |
| SCHEMBL20141901 | 0.76 | ATG7 (1.00) | ATG7 | |
| SCHEMBL20141963 | 0.74 | ADK (0.77) | ATG7ADK | |
| SCHEMBL20141562 | 0.74 | ADK (0.77) | ATG7ADK | |
| SCHEMBL25296572 | 0.72 | CA2 (0.62) | ADK | |
| SCHEMBL19547898 | 0.71 | CA2 (0.49) | ADK | |
| SCHEMBL20141727 | 0.71 | ATG7 (0.50) | ATG7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089786-A1 | ATG7 INHIBITORS AND THE USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |