Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG7 | O95352 | 17/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141727 | 0.88 | ATG7 (0.50) | ATG7RXFP1 | |
| SCHEMBL20142034 | 0.82 | ATG7 (0.61) | ATG7 | |
| SCHEMBL20142322 | 0.77 | ATG7 (0.70) | ATG7RXFP1 | |
| SCHEMBL20142351 | 0.75 | PI4KA (0.62) | ATG7RXFP1PI4KAPI4K2BPI4K2A | |
| SCHEMBL20142202 | 0.72 | ATG7 (0.63) | ATG7 | |
| SCHEMBL20141736 | 0.71 | ATG7 (0.62) | ATG7 | |
| SCHEMBL20142044 | 0.69 | ATG7 (0.58) | ATG7RXFP1PI4KAPI4K2BPI4K2A | |
| SCHEMBL20142147 | 0.69 | ATG7 (0.74) | ATG7RXFP1 | |
| SCHEMBL20142135 | 0.69 | PI4KA (0.59) | ATG7RXFP1PI4KAPI4K2BPI4K2A | |
| SCHEMBL20141719 | 0.69 | ATG7 (0.72) | ATG7RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089786-A1 | ATG7 INHIBITORS AND THE USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |