Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142085 | 0.81 | KLKB1 (0.30) | DGAT1KLKB1 | |
| SCHEMBL20139753 | 0.73 | SUV39H2 (0.43) | — | |
| SCHEMBL20139752 | 0.73 | SUV39H2 (0.43) | — | |
| SCHEMBL20141793 | 0.73 | SUV39H2 (0.43) | — | |
| SCHEMBL20141790 | 0.72 | SLC16A3 (0.33) | DGAT1 | |
| SCHEMBL4589906 | 0.69 | PSMB5 (0.34) | — | |
| SCHEMBL4589908 | 0.69 | PSMB5 (0.34) | — | |
| SCHEMBL20157182 | 0.67 | SUV39H2 (0.43) | — | |
| SCHEMBL29925168 | 0.67 | HTR2C (0.48) | DGAT1NPC1 | |
| SCHEMBL28840671 | 0.67 | HTR2C (0.48) | DGAT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |