Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.53 |
| ▸ | DCLRE1B | Q9H816 | 3/20 | 0.47 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356669 | 0.81 | FOLH1 (0.70) | FOLH1DCLRE1BDCLRE1AHMGB1ALDH1A1 | |
| Benzene SCHEMBL1931924 | 0.81 | FOLH1 (0.70) | FOLH1DCLRE1BDCLRE1AHMGB1ALDH1A1 | |
| SCHEMBL2651867 | 0.80 | FOLH1 (0.56) | FOLH1DCLRE1BDCLRE1AHMGB1ALDH1A1 | |
| Methane SCHEMBL6534805 | 0.78 | HMGB1 (0.61) | FOLH1DCLRE1BDCLRE1AHMGB1ALDH1A1 | |
| SCHEMBL7963839 | 0.78 | FOLH1 (0.52) | FOLH1DCLRE1BDCLRE1AHMGB1ALDH1A1 | |
| SCHEMBL28329450 | 0.77 | FOLH1 (0.70) | FOLH1HMGB1ALDH1A1ALOX15MAPT | |
| SCHEMBL1931921 | 0.76 | DCLRE1B (0.56) | FOLH1DCLRE1BDCLRE1AALDH1A1ALOX15 | |
| SCHEMBL578127 | 0.75 | CLCN2 (0.56) | FOLH1HMGB1ALDH1A1ALOX15CLCN2 | |
| SCHEMBL27669308 | 0.75 | FOLH1 (0.62) | FOLH1HMGB1ALDH1A1ALOX15MAPT | |
| SCHEMBL330503 | 0.75 | IDO1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986153-A | Ionizable cationic lipid compound, and preparation method and application thereof | 晟迪生物医药(苏州)有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-117866042-A | Disulfide-containing cell penetrating peptides and methods of making and using the same | 俄亥俄州国家创新基金会 | 2024-04-12 | — | — | CN | disclosed |
| US-11878046-B2 | Di-sulfide containing cell penetrating peptides and methods of making and using thereof | OHIO STATE INNOVATION FOUNDATION (US) | 2024-01-23 | — | — | US | disclosed |
| CN-110114075-B | Disulfide-containing cell penetrating peptides and methods of making and using the same | 俄亥俄州国家创新基金会 | 2024-01-12 | — | — | CN | disclosed |
| US-11351222-B2 | Di-sulfide containing cell penetrating peptides and methods of making and using thereof | OHIO STATE INNOVATION FOUNDATION (US) | 2022-06-07 | — | — | US | disclosed |
| US-20220160819-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-05-26 | — | — | US | disclosed |
| US-20190282654-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2019-09-19 | — | — | US | disclosed |
| EP-3538125-A2 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | Ohio State Innovation Foundation (US) | 2019-09-18 | — | — | EP | disclosed |
| CN-110114075-A | Disulfide-containing cell penetrating peptides and methods of making and using the same | 俄亥俄州国家创新基金会 | 2019-08-09 | — | — | CN | disclosed |
| WO-2018089648-A2 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2018-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190282654-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | IKBKE, IKBKB, SHARPIN | FOLH1 1375/4885DCLRE1B 604/4885DCLRE1A 113/4885 |
| US-11878046-B2 | Di-sulfide containing cell penetrating peptides and methods of making and using thereof | IKBKE, IKBKB, SHARPIN | FOLH1 1375/4885DCLRE1B 604/4885DCLRE1A 113/4885 |
| US-20220160819-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | IKBKE, IKBKB, SHARPIN | FOLH1 1375/4885DCLRE1B 604/4885DCLRE1A 113/4885 |
| US-11351222-B2 | Di-sulfide containing cell penetrating peptides and methods of making and using thereof | IKBKE, IKBKB, SHARPIN | FOLH1 1375/4885DCLRE1B 604/4885DCLRE1A 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.