Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCLRE1B | Q9H816 | 3/20 | 0.56 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.53 |
| ▸ | HNF4A | P41235 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 3/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29254314 | 0.84 | CLCN2 (0.54) | FOLH1HNF4AALDH1A1ALOX15MAPT | |
| SCHEMBL3843394 | 0.84 | HNF4A (0.55) | FOLH1HNF4AALDH1A1ALOX15MAPT | |
| SCHEMBL6782256 | 0.82 | HNF4A (0.49) | DCLRE1BDCLRE1AFOLH1HNF4AALDH1A1 | |
| SCHEMBL2356669 | 0.81 | FOLH1 (0.70) | DCLRE1BDCLRE1AFOLH1ALDH1A1ALOX15 | |
| Benzene SCHEMBL1931924 | 0.81 | FOLH1 (0.70) | DCLRE1BDCLRE1AFOLH1ALDH1A1ALOX15 | |
| SCHEMBL70098 | 0.80 | HNF4A (0.63) | HNF4AALDH1A1ALOX15MAPTKDM4E | |
| SCHEMBL8653763 | 0.78 | FOLH1 (0.45) | DCLRE1BDCLRE1AFOLH1HNF4AALDH1A1 | |
| SCHEMBL28391136 | 0.77 | HNF4A (0.59) | HNF4AALDH1A1ALOX15MAPTKDM4E | |
| SCHEMBL4826258 | 0.76 | BID (0.52) | ALOX15MAPTKDM4E | |
| SCHEMBL2651867 | 0.76 | FOLH1 (0.56) | DCLRE1BDCLRE1AFOLH1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110130482-A1 | Process for preparing armatic thiophenyl ketones | PRETOR ROGER | 2011-06-02 | — | — | US | claimed |
| EP-1799638-B1 | PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES | CIBA HOLDING INC (CH) | 2008-07-30 | — | — | EP | claimed |
| EP-1799638-A1 | PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-06-27 | — | — | EP | claimed |
| WO-2006034966-A1 | PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-04-06 | — | — | WO | claimed |
| US-20110130482-A1 | Process for preparing armatic thiophenyl ketones | PRETOR ROGER | 2011-06-02 | — | — | US | disclosed |
| EP-1799638-B1 | PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES | CIBA HOLDING INC (CH) | 2008-07-30 | — | — | EP | disclosed |
| EP-1799638-A1 | PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006034966-A1 | PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-04-06 | — | — | WO | disclosed |
| EP-0003771-B1 | CARBOSTYRILE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1982-10-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130482-A1 | Process for preparing armatic thiophenyl ketones | ACOT7, AGPAT2, COASY | DCLRE1B 4663/4885DCLRE1A 4716/4885FOLH1 3847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.