Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15818525 | 0.71 | SLC2A1 (0.64) | SLC2A1KDM4EALDH1A1KMT2ACYP46A1 | |
| SCHEMBL2021978 | 0.67 | FLT1 (0.45) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL14315496 | 0.67 | MAPK14 (0.54) | MAPTGAAMAPK13KDM4EALDH1A1 | |
| SCHEMBL3187202 | 0.66 | KDM4E (0.48) | MAPTGAAKDM4EALDH1A1GLA | |
| SCHEMBL18357422 | 0.65 | DAPK3 (0.41) | MAPTGAAKDM4EALDH1A1GLA | |
| SCHEMBL3207481 | 0.65 | MAPT (0.47) | MAPTGAAKDM4EALDH1A1GLA | |
| SCHEMBL2430255 | 0.65 | KDM4E (0.50) | MAPTGAAKDM4EALDH1A1GLA | |
| SCHEMBL20140774 | 0.64 | GSK3B (0.38) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL30980408 | 0.64 | ALDH1A1 (0.41) | GAAKDM4EALDH1A1GLAMEN1 | |
| SCHEMBL18420354 | 0.62 | HTR2A (0.43) | MAPTSLC2A1KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |